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  • in reply to: Allopurinol and ACE inhibitors #8787
    sputnik
    Participant

    Well the Sulfinpyrazole (Anturane) worked very well on two 100 mg tablets per day and got me to 4.8 – 6 mg/dl UA readings most days without side effects.  Unfortunately on attempting to get my second prescription I was told the manufacturers has stopped making it! I was then prescribed Alllopurinol (by a different Doctor). Not so good, harder to control UA level on 200mg per day so far and side effects of bad stomach cramps and general aches. I returned to the Doctor and asked about Febuxostat but she wasn't aware of this alternative and said it couldn't be prescribed. I understand from my own internet research that it was recently licensed for use in UK for patients not able to tolerate allopurinol. She would not search the internet which is annoying as this is the first thing my local practice Doctors usually look at. Does anyone know the availability of this drug in the UK and has anyone experiencing allopurinol side effects tried Febuxostat without problems?

    Thanks

    in reply to: Allopurinol and ACE inhibitors #8084
    sputnik
    Participant

    Thanks zip2play

    I also had the ACE cough but nowhere near as bad as you and it gradually went after about a month. I will update the thread after I have started the sulfinpyrazone and established the dose I need to reduce to 6mg/dl UA or below, assuming no serious side effects of course. This is now the third “lifetime drug” I will be taking, along with ramipril and simvastatin for high triglycerides. I hope this cocktail is not antagonistic. At least we are doing our bit for research!!

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