[Raj Barua]

Keith, thanks for your advice. My LFT is a bit abnormal as of now. So the doc has adviced me not to have NASID’s(only SOS). Although the knee has cleared up, within two days of the knee clearing up I had an attack on my left toe. I am continuing wiith alluprunoil and had colchicine for initial day or two of this flare up.

Two days ago there was a lot of swelling on the toe, although the swelling has reduced there is pain. Its been almost seven days since this flare up

[Raj Barua]

Keith, Colchicine was prescribed but the doctor has asked me to stop taking it as it not very nephro friendly. So with the NASID’s.

I have been asked to discontinue alluprunoil and shift to febuxstat (which according to him is more nephro friendly)and my current uric acid readings as of yesterday is 3.9.

But there is still pain whn i try to walk or bend my knee, and general knee immobility. But there is no acute pain.

My doc has reccomended that because of my LFT and Kidney test I have no choice but to wear the gout out.

Yes I have started drinking skimmed milk. But why have you reccomended that I keep my fluid (water) intake only to 2.5-3 lts. I always though that more the intake the better it is to flush out uric acid.

Best
RB

[Raj Barua]

Yes, my attacks have been spreading from one area to anohter area in the same knee. Keith, thanks for your support. I am continuing with alluprunoil and colchicine. I am not taking any NASID’s as the pain is bearable. However once in four to five days it really falres up that’s when I gulp a voveran tablet.

But should I continue with NASID’s since it will act as an anti inflamatory, none of the NASID’s (brufen, naproxen) are working. I am scared that NASID’s may affect my kidneys.
And I am alergic to the cox inhibitors which I presume does not have a FDA clearence in the US.

[Raj Barua]

Ok had to bite the bullet, started with Colchicine and Voveran 75 mg. I m still perplexed why another flare up especially when my uric acid is at 4.4 that is below 5.

Is it because my old crystals in the knee are dissolving. It is in the different areas of the knee.

[Raj Barua]

Thanks, I m continuing with allupronoil, but have had another attack on the knee again from last night. I m at my wits end because my serum level is 4.4. I had some tofu with black bean sauce, could that have possibly triggered it.

I m drinking lots of water not taking Colchicine or NASIDs because of my liver. Just biting my teeth and continuing with 300 mg of allupronoil. This too shall pass

[Raj Barua]

Keith & Cujo,

Thanks for your comments. The acute flare up and pain is over, the knee continues to hurt and is still somehow stiff. Sometimes at night the pain increases, and it does go down when I gulp down some baking poweder or eat an apple. I have noticed that if there is increase in acidity then the pain tends to increase.

My last uric acid level was 4.4 yesterday and about 5.4 about four days ago. I am still on allouprunoil 300 mg a day. I have stopped coclchicine and NASID’s. My liver function test were not good SGPT, SGOT and GGTP were on the higher side.

I just hope that allouprunoil does not cause any further damage to my liver.

Should I continue with 300 mg of allouprunoil or should i lessen the dosage to about 200 mg since my serum levels are down.

Have I injuried any tendon or cartillage in my knee becuase of which it still hurts and is sore or is it my crystals disolving.

I also beleive that baking soda helps to neutralize the acidity, that is a key aspect.

Thanks

[Raj Barua]

I have had readings upto 13.5, that was couple of years ago. A few days ago I had a reading of 9.2…. Then 7.2

[Raj Barua]

Ok another acute flare up in my knees… Had some lentil soup that might have triggered it… Started with allupronoil 100mg, Colchicine and brufen…

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