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Is it innevitable that I will experience side effects using this drug. Some web sites suggest that 80% do. How often are these serious and is it worth the risk.
Is there any alternative (in the UK) and would the gout attack subside naturally but take longer.
BTW where is the search facility on this BB. I canot sem to find it. Cheers.
I started on it the 16th of June taking one 0.6mg tablet twice a day. The first few days it didn't seem to bother me at all but after that. I've been running to to bathroom two or three times a day. I was hoping that my body would ajust to it but that hasn't happened. But if it will hold off the pain and swelling I guess I'll take the trade off for a while till I get the full effects of the ALLOP. This is the only side effect I've had. Of course everybody reacts different to meds. If you give it a try I hope you do ok on it . Also i couldn't find a way to do a search on here either. Maybe someone else can help with that. Good luck. Limpy
Colchicine is a potent laxative. You might not notice one pill per day.
Two pills a day will keep you VERY regular, if slightly more so.
Therapeutic doses of 8, 12, or 16 pills in a single dose (or as I stupidly did…22) for a massive acute attack will cause horrific diarrhea that lasts a day. The diarrhea and the stoppage of pain often seem to go hand in hand…a seeming dependence?
As soon as the diarrhea started for me, nine days of excruciating pain instantly came to a halt.
So if you want to call it a side effect, yes, probably 100% of colchicine users will experience it. I prefer to think of it as an EFFECT.
My theory is that colchicine causes an IMMENSE loss of body fluids and thus reduces the edema in a painful swelling and that is part of the cure (Be curious to try a whole bar of Ex-Lax and see if it has the same effect.). Accepted theory is that colchine alkalyzes an acidic joint, stopping the laying down of more uric acid, thus stopping the attack.
What is most important is that, whatever the methodology, IT WORKS.
As I have not suffered from the runs and my pain has only ben relieved by perhaps 50% after 11 tablets, do you think a) I have been given the wrong tablets by pharmacy b) I am just one of those that it cannot help c) it may start to work after my last tablet d) I will have to wait a few days before I restart the Colchinine and then it will worlk.
BTW my pills are the smallest tablets I have ever seen – slightly larger that a pin head. Does that sound right.
I have to admit that I have not just been sitting around. Is total rest a prerequirement of the tablets?
Caveman, I take 0.60 Colchicine tablets. There a little smaller then the end of a eraser on a pencil and alot bigger than a pin head. I would make a trip back to the drug store to make sure they gave you the right meds. I'm sure if I took as many of these as you have I'd be camped in the bathroom. Good luck. LIMPY
Thanks limpy. I did return to the chemist and confirmed that they are correct. Obviously the 500 mcg tablets are tiny in UK. So they are the right pills,just don't work.
Do you think that I could have hindered their effectiveness by being mobile.
Caveman, I have no idea why they don't work for you. I hope someone else will chime in here. Good luck. LIMPY
Caveman,
Mine are close to the size of a pinhead…dosage 1/2 mg. I guess it there were no additives, the active dose could be in a pill the size of a pin POINT.
As I have not suffered from the runs and my pain has only ben relieved by perhaps 50% after 11 tablets,
Tough to say becasue I have only ONCE taken a THERAPEUTIC dose for an acute attack and I toolk 22 pills before the co-occurrence of vicious diarrhea and pain relief. My GUESS is that the 11 you took were not enough. I know I cannot make too much from my ONE trial of this megadose…but the effect was truly startling.
The old remedy that I believe in, from the Physician's Dest Reference of 1976 is”
Two to start and one an hour until paiin relief, signiificant diarrhea, or 16 pills. By that standard you stopped a bit too soon.
Why did you stop?
zip2play said:
Post edited 5:21 pm – July 6, 2010 by zip2play
Caveman,
Mine are close to the size of a pinhead…dosage 1/2 mg. I guess it there were no additives, the active dose could be in a pill the size of a pin POINT.
…
Zip, I know you live in the States, so what kind of “Colchicines” did you take/buy?? 1/2mg and pinhead size??? My Colchicines have been .6mg and the size of your smiley
for more than 26 years to this very day.zip
I was told by the GP to take one 500 mcg tablet up to four times a day but not more than 12 tablets in one course. Then leave for 3 days and resume again if pain persists. I have read this is the prescribed dosage in the UK. I have now completed that first course and am 80% free of pain and no swelling. The only pain I still have is on the bunion and ball of foot. With any luck I hope to be OK in the morning. OR wait till Friday to resume tablets.
As I have said in previous posts, I don't know if I hindered a quicker relief by being mobile. Is rest that important for the pills to work?
BTW after 12 tablets I still have no runs. Fancy praying for the trots. Kinky eh?
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