Water Kills Gout Pain 3 Ways

by KeithTaylor Comment Closed
Thanks to WouteR for this imageGout sufferers know how good water is. Water reduces uric acid concentration, lowering the risk of pain-inducing crystals forming. Water helps flush excess uric acid, and many toxic gout treatments, from the body. Two benefits for a gout remedy are good. Where's the third one coming from? I've had a recent email exchange with a long-term gout sufferer who reckons he has found a new way to combat gout with water. (more…)...
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Bugged By Gout

by KeithTaylor Comment Closed
Xanthine oxidase reduction by quercetin fascinates me. Can tea, onions, apples and other foods hold the secret for natural gout cures? Lots of scientists are looking, but extracting the active ingredients is hard. This is really bugging me! But, could bugs be the answer? Quercetin is a member of the flavonoid group of compounds. These compounds occur naturally in plants, and have been shown to have properties that are beneficial to health. Quercetin has been studied in several recent investigations to assess it's ability to inhibit xanthine oxidase (XO). Both allopurinol and febuxostat work by XO inhibition. Unfortunately, the quercetin studies are largely confined to laboratory experiments with occasional animal tests. Animal tests so far have not shown success, and this appears to be down to solubility of quercetin. Just as I thought I had finished reviewing relevant research, I spotted a mention of quercetin buried deep in a study of large cabbage white caterpillars. So deep, that I cannot assess if quercetin is actually...
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New Gout Treatment Goes To Trial

by KeithTaylor Comment Closed
US biotech firm BioCryst Pharmaceuticals, Inc recently announced the initiation of a Phase 2 human clinical trial of the drug candidate BCX4208 in patients suffering from gout. BCX4208, co-developed by New Zealand crown research institute IRL, is a next generation purine nucleoside phosphorylase (PNP) inhibitor, which a recent study shows may have utility in diseases dependent on T-cells, B-cells or uric acid. The latest trial is designed to determine the effect of different doses of orally administered BCX4208 on uric acid levels in the blood, the build-up of which can lead to the often painful condition known as gout. BCX4208 differs from existing gout treatments in that it targets an enzyme known as PNP (purine nucleoside phosphorylase). This novel mechanism gives the drug candidate the potential to address unmet medical needs across a broad spectrum of inflammatory diseases in which this enzyme plays a role. It has the potential for once-a day dosing suitable for chronic administration and has been shown...
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Gout Doctor Required

by KeithTaylor Comment Closed
Do you know a good gout doctor? It could be a gout specialist, e.g. a rheumatologist, or it could be your local MD who has given you great gout treatment. Prompted by a tidying up of old forum discussions, I notice that there are occasional calls for recommendations for a doctor with good gout knowledge. Rarely are these answered, but some of that may be due to the way topics that ask that question are scattered over many forums. I've decided to try and build a list of recommended gout doctors, and I can only do it with your help. If your doctor is particularly good with gout, please pass on their details, but first contact them to check this is OK. I will start a new list organized by country and region with the details. Similarly, if you are looking for a gout specialist, please say which area you are prepared to travel to. To kick things off, the old message that I have...
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Gout Pain Relief

by KeithTaylor Comment Closed
Gout pain relief is the first stage of gout management. The second stage is treatment to reduce uric acid, but this can cause more pain and many people miss this vital treatment because they cannot tolerate the pain. Recent discoveries regarding gout pain have suggested an alternative approach that may well lead to a new, more effective form of gout pain relief. Many people mistakenly believe that uric acid crystals, commonly described as needle-like, cause pain in the same way that sticking pins in your body will. If you've studied my U-D-R-P model of gout pain, you will know that it is actually your immune system reacting to the crystals that causes swelling and pain in a similar way to fighting a virus. And the pain doesn't only arise when something triggers these uric acid crystals to form. A few days after your immune system has attacked uric acid crystals, swelling and pain subside as the crystals become hidden by white...
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Unusual Hip Gout

by Al O'Purinol Comment Closed
I am a female my weight now is 105 lbs, I have always fought a low body weight and ate any and everything to keep weight on. I ate canned sardines and oysters; I love liverwurst!! 5 years ago I had severe pain in my hip for over a year (to the point of being disabled to work) and finally convinced my doctor to test my uric acid since gout runs in my family He argued that gout does not happen in the hip. (11.6 was the outcome). My history is of being a commercial fishing captain where I sit in a chair with my feet propped out the window and my but being to lowest center of gravity. My questions: How often does gout occur in only the hip? When it lasted as long as it did is there anything to help my hip (I rarely have flareups of gout but have constsnt pain from the prolonged gout)? I can not...
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Clinical Research for Gout – San Antonio, TX

by KeithTaylor Comment Closed
Radiant Research in Texas have announced a new gout investigational medicine research project. View Larger Map Details are few, but the researchers are looking for participants who experience occasional gout flares. Qualified participants will receive all study related care and investigational medication at no charge and may be compensated up to $350 for time and travel. (more…)...
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