Is Gout Inherited?

We often wonder, is gout inherited?

I’m working on guidelines for inherited gout. We often call this hereditary gout or genetic gout. For the moment, the best factual information is Is Your Gout Hereditary?. This, and similar information form the basis of my Gout Symptoms Guidelines, especially Why do I have Gout?.

We can see that gout is often, but not always, inherited. Obviously, you cannot change your parents. But you should understand what hereditary gout means for you. Therefore, note we have three interchangeable terms (hereditary gout, genetic gout, and inherited gout). Then use the search box at the top of the page to search for each of these terms. Or, do a combined search by copying hereditary gout|genetic gout|inherited gout into the search box.

Better Gout Treament

Starting Allopurinol

Starting allopurinol is a worrying move for most gout sufferers.

First, there’s the psychological trauma of committing to a daily pill for the rest of your life.

Second, there’s the worry of the risk of horrendous side affects that affect some allopurinol users.

Third, there’s more worry about gout attacks during the first few months of allopurinol usage.

These are the 3 main concerns that gout sufferers ask about in the gout forums. There are many other concerns about starting allopurinol, such as getting the right dose, or if allopurinol should be started during a gout flare. My main concern is that gout patients do not seem to get the right answers from their doctors.

Whatever concerns you might have about starting allopurinol, you can be certain you will get good advice in the gout forum. Your best place to start is by reading my allopurinol guidelines. My guidelines give you all the facts you need about allopurinol. If you are specifically looking for information about the best way to start taking allopurinol, then I suggest you search for starting allopurinol.


High Uric Acid Levels

High uric acid levels cause gout. But what does high really mean?

What is high for one person, might be acceptable for another. So, the important question is: What are Your high uric acid levels?

You need to know what is a high number for you, then you can find ways to lower uric acid to an acceptable level. I describe all the facts you need to know in my uric acid guidelines. However, there are also many facts that are not relevant to you. Here on GoutPal Interactive, I help you to ask your doctor the right questions about uric acid. I also help you understand your doctor’s answers and recommendations.

If you are worried about high uric acid levels, the best thing to do is ask your uric acid question. In your question, you should include as much uric acid test result history as you can. In fact, it is a good idea to add your uric acid test results to your personal gout profile as soon as you get them. If you do not have those numbers, please ask your doctor when you visit, or by email. Your blood test results say more about your high uric acid levels than anything else.

An alternative to starting your own discussion, is to join in an existing discussion. The relevant discussions are labeled what is considered a high uric acid level. You can see from these discussions that it is easy to manage gout when you recognize your high uric acid levels, then take steps to lower them.

Please note that I’m moving my gout forums to a new website. See the latest High Uric Acid Levels discussions in my Gout Topic Index. Join in any of those topics, or start your own new High Uric Acid Levels discussion.


Gout Study Information

This is a summary of discussions about gout study information. It helps you find archived gout studies and current gout research discussions.

GoutPal’s Gout Study Information

When gout study information helps with better gout guidelines, I update the gout website with these new gout facts. For significant new gout research, I might also write a new gout blog article.

Other research generates information that is ongoing, or insufficient evidence to improve guidelines. In these cases, we discuss the likely impact generally, or personally, on our gout.

Gout Symptoms And Causes Forum

What are your Gout Causes?

On many levels, gout causes are simple. It is simply excess uric acid that causes gout.

I’ve recently started reorganizing my gout causes pages, and I want to make sure I have not missed any. Also, there has not been much discussion of gout causes recently, so this is the place to discuss any aspects of the causes of gout.

Please note that I am not particularly interested here in what causes a single gout flare. I am interested in the underlying causes of gout. My list so far is:

  • Kidney disease
  • Surgery
  • Leukemia, lymphoma, or hemoglobin disorders
  • Medical conditions that cause rapid weight change (increase or decrease)
  • Medications for other health conditions
  • Exposure to lead and other metal salts

Can you think of others?

What are your feelings on obesity? I believe that diet can play a part, and I would add that starvation, dehydration, and malnutrition can also affect gout. I am certainly not interested in specific foods, but have you ever cured gout by completely stopping a bad aspect of diet? To qualify for that, you need to demonstrate uric acid over 6.5 being reduced to 5 or below. This is important, because stopping the pain is not enough – uric acid crystals continue to grow slowly, and they will destroy your joints, kidneys, and other organs, which is definitely not a gout cure.

Please see my article, Gout Causes: Why Does It Matter?, and the What Causes Gout guidelines, for more details of exactly what I mean.

Leave What are your Gout Causes? to browse the What Causes Gout guidelines

Gout Remedies Forum For Gout Treatment

Allopurinol and ACE inhibitors

In conjunction with my reorganization of my Allopurinol And Other Medicines pages, I have moved an old forum message here.

Please join the discussion if you have any questions, opinions, or experiences of allopurinol with other medicines for high blood pressure.

The earlier discussion started with sputnik from UK asking:

After being diagnosed last year and having had three attacks of gout I bought a uric acid monitor and presented three months of tests to the Doctor today. (Average reading 8.9mg/dl).

I said that I would like to be treated with medication that reduced the amount of uric acid rather than with anti inflammatories that I consider only mask the real problem. My father was not treated properly for years and now has kidney disease that prevents him taking allopurinol etc.

The doc agreed to treat me but prescribed sulfinpyrazone rather than allopurinol as I am also taking 10mg Ramipril daily for high BP. Apparently there is a (low) risk of allopurinol causing reactions with ACE inhibitor medication. This seems to work differently to allopurinol by increasing excretion of UA rather than reducing its production.

I have a blood test booked next week to correlate my readings with a lab result and then start the sulfinpyrazone in gradually increasing doses until reading is within normal range. All these drugs carry the risk of side effects so does anyone have more information on what is the best treatment?

Gout Remedies Forum For Gout Treatment

Allopurinol And Azathioprine

Allopurinol is great for gout patients, but what if you have other diseases?

Over the years, we have had several discussions about other diseases because many gout sufferers have other health problems.

One significant is the use of allopurinol for kidney transplant patients. Azathioprine (commonly sold as Imuran, or Azasan) is commonly used to control rejection of transplanted organs.

It has been said that allopurinol should be avoided for patients taking azathioprine, but there is no clear view.

I have not researched this much, as it is very specialist, but perhaps gout patients who are affected by this may share experiences or have better information.